- Kunzendorf U, Karch H, Werber D, Haller H. (2011). Recent outbreak of hemolytic uremic syndrome in Germany. Kid Int. 80(9):900-2.
- Joseph A, et al. (2020). Shiga Toxin-Associated Hemolytic Uremic Syndrome: A Narrative Review. Toxins. 12(2):67.
- Karmali MA. (2009). Host and pathogen determinants of verocytotoxin-producing Escherichia coli-associated hemolytic uremic syndrome. Kid Int. 75(Supp. 112):S4-S7.
- Tarr PI, Gordon CA, Chandler WL. (2005). Shiga-toxin-producing Escherichia coli and hemolytic uraemic syndrome. Lancet. 365(9464):1073-86.
- Croxen A, et al. (2013). Recent Advances in Understanding Enteric Pathogenic Escherichia Coli. Clin Microbiol Rev. 26(4):822-80.
- Andreoli SP, Zimmerhackl LB. Hemolytic uremic syndrome. In: Geary DF, Shaefer F, eds. Comprehensive Pediatric Nephrology 1st ed, Philadelphia, PA: Mosby, Elsevier; 2008.
- Kemper MJ. (2012). Outbreak of hemolytic uremic syndrome caused by E. Coli O104:H4 in Germany: a pediatric perspective. Pediatr Nephrol. 27(2):161-4.
- Liu Y, et al. (2011). Shiga Toxin Type 2 (Stx2), a Potential Agent of Bioterrorism, Has a Short Distribution and a Long Elimination Half-Life, and Induces Kidney and Thymus Lesions in Rats. Arch Toxicol. 85(9):1133-40.
- Qin J, et al. (2011). Identification of the Shiga Toxin-Producing Escherichia coli O104:H4 Strain Responsible for a Food Poisoning Outbreak in Germany by PCR. J Clin Microbiol. 49(9):3439-40.
- Bell BP, et al. (1997). Predictors of hemolytic uremic syndrome in children during a large outbreak of Escherichia coli O157:H7 infections. Pediatrics. 100(1):E12.
- Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI. (2000). The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med. 342(26):1930-6.
- Safdar N, Said A, Gangnon RE, Maki GD. (2002). Risk of hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 enteritis: a meta-analysis. JAMA. 288(8):996-1001.
- Amerling R, Ronco C, Winchester J. (2012). Continuous Flow Peritoneal Dialysis: Update 2012. Contrib Nephrol. 178:205-15.
- Walsh PR, Sally J. (2019). Eculizumab in the treatment of Shiga toxin haemolytic uraemic syndrome. Pediatr Nephrol. 34(9):1485-92.
- Menne J, et al. (2012). Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study. BMJ. 345:e4565.
- Kielstein JT, et al. (2012). Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic-uraemic syndrome: an analysis of the German STEC-HUS registry. Nephrol Dial Transplant. 27(10):3807-15.
- Sheoran AS, et al. (2005). Human antibody against shiga toxin 2 administered to piglets after the onset of diarrhea due to Escherichia coli O157:H7 prevents fatal systemic complications. Infect Immun. 73(8):4607-13.
- Khalid M, Andreoli S. (2018). Extrarenal Manifestations of the Hemolytic Uremic Syndrome Associated With Shiga Toxin-Producing Escherichia Coli (STEC HUS). Pediatr Nephrol. 34(12):2495-507.
- Goldstein SL. (2012). Acute Kidney Injury in Children and Its Potential Consequences in Adulthood. Blood Purif. 33(1-3):131‐7.
- Siegler RL, Pavia AT, Cook JB. (1997). Hemolytic-uremic Syndrome in Adolescents. Arch Pediatr Adolesc Med. 151(2):165‐9.
- Siegler RL, et al. (1991). Long-term Outcome and Prognostic Indicators in the Hemolytic-Uremic Syndrome. J Pediatr. 118(2):195‐200.
- Tremblay JM, et al. (2013). A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2. Infect Immun. 81(12):4592-603.
- Agbas A, et al. (2018). Outbreak of Shiga toxin-producing Escherichia-coli-associated hemolytic uremic syndrome in Istanbul in 2015: outcome and experience with eculizumab. Pediatr Nephrol. 33(12):2371-81.
- Weil BR, Andreoli SP, Billmire DF. (2010). Bleeding risk for surgical dialysis procedures in children with hemolytic uremic syndrome. Pediatr Nephrol. 25(9):1693-8.
- Andreoli SP, Bergstein JM. (1982). Development of insulin-dependent diabetes mellitus during the hemolytic-uremic syndrome. J Pediatr. 100(4):541-5.
- Burns JC, Berman ER, Fagre JL, Shikes RH, Lum GM. (1982). Pancreatic islet cell necrosis: association with hemolytic-uremic syndrome. J Pediatr. 100(4):582-4.
- Andreoli S, Bergstein J. (1987). Exocrine and endocrine pancreatic insufficiency and calcinosis after hemolytic uremic syndrome. J Pediatr. 110(5):816-7.
- Nesmith JD, Ellis E. (2007). Childhood hemolytic uremic syndrome is associated with adolescent-onset diabetes mellitus. Pediatr Nephrol. 22(2):294-7.
- Schlieper A, et al. (1999). Neuropsychological sequelae of haemolytic uraemic syndrome. Arch Dis Child. 80(3):214-20.
- Qamar IU, et al. (1996). Long-term neurological sequelae of hemolytic-uremic syndrome: a preliminary report. Pediatr Nephrol. 10(4):504-6.
- Bauer A, et al. (2014). Neurological involvement in children with E. coli O104:H4-induced hemolytic uremic syndrome. Pediatr Nephrol. 29(9):1607-15.
- Oakes RS, Kirkham JK, Nelson RD, Siegler RL. (2008). Duration of oliguria and anuria as predictors of chronic renal-related sequelae in post-diarrheal hemolytic uremic syndrome. Pediatr Nephrol. 23(8):1303-8.
- Gagnadoux MF, et al. (1996). Long-term (15-25 Years) Outcome of Childhood Hemolytic-Uremic Syndrome. Clin Nephrol. 46(1):39-41.
- Calletti MG, Gallo G, Gianantonio CA. (1996). Development of Focal Segmental Sclerosis and Hyalinosis in Hemolytic Uremic Syndrome. Pediatr Nephrol. 10(6):687-92.
- Fitzpatrick R. (1991). Surveys of patients satisfaction: I-- Important general considerations. BMJ. 302(6781):887-9.
- Tonshoff B, et al. (1994). Outcome and prognostic determinants in the hemolytic uremic syndrome of children. Nephron. 68:63–70.
- Calderon-Margalit R. (2018). History of Childhood Kidney Disease and Risk of Adult End-Stage Renal Disease. N Engl J Med. 378:428-38.
- Ingelfinger JR. (2018). A Disturbing Legacy of Childhood Kidney Disease. N Engl J Med. 378:470-1.
- Martin-Navarro JA, et al. (2013). Long-term renal prognosis of typical haemolytic-uremic syndrome suffered in infancy. Nefrologia. 33(3):433-5.
- Vaterodt L, et al. (2018). Short- and Long-Term Renal Outcome of Hemolytic-Uremic Syndrome in Childhood. Frontiers in Pediatrics. 6:220.
- Mammen C, et al. (2012). Long-term Risk of CKD in Children Surviving Episodes of Acute Kidney Injury in the Intensive Care Unit: A Prospective Cohort Study. Am J Kidney Dis. 59(4):523-30.
- Heung M, Chawla LS. (2012). Predicting Progression to Chronic Kidney Disease After Recovery From Acute Kidney Injury. Curr Opin Nephrol Hypertens. 21(6):628-34.
- Monet-Didailler C, et al. (2019). Long-term Outcome of Diarrhea-Associated Hemolytic Uremic Syndrome Is Poorly Related to Markers of Kidney Injury at 1-year Follow-Up in a Population-Based Cohort. Pediatr Nephrol. 34(4):657-62.
- Small G, Watson AR, Evans JH, Gallagher J. (1999). Hemolytic Uremic Syndrome: Defining the Need for Long-Term Follow-Up. Clin Nephrol. 52(6):352-6.
Foodborne Illnesses / Hemolytic Uremic Syndrome /
HUS References
Outbreaks and recalls
March 26, 2023
E. coli recall linked Elkhart Valley Packing
Elkhorn Valley Packing, a Harper, Kan. establishment, is recalling approximately 3,436 pounds of boneless beef chuck product that may be contaminated with Shiga toxin-producing E. coli (STEC) O103, the U.S...
January 06, 2023
Bill Marler: Taking on E. coli, Big Ag, Raw Milk Conspiracy Theorists and the USDA
In yesterday’s post, I wrote about Bill Marler, the influential, outspoken, high-profile attorney who is representing Stephanie Smith in her $100 million lawsuit against Cargill. Smith, an ex-dance instructor from...
December 11, 2022
What You Should Know About E. coli in Manure
E. coli O157:H7 bacteria and other pathogenic E. coli mostly live in the intestines of cattle, but E. coli bacteria have also been found in the intestines of chickens, deer...
December 07, 2022
POISONED: The True Story of the Deadly E. Coli Outbreak That Changed the Way Americans Eat.
At the end of 1992, Jack in the Box was the fifth-largest fast-food chain in the country, courting the market with the Monster Burger and its soon-to-be-immensely-regretted slogan, “So good...