--- title: How is Cyclospora Diagnosed? date: 2020-12-16T17:28:00-08:00 author: admin canonical_url: "https://marlerclark.com/foodborne-illnesses/cyclospora/how-is-cyclospora-diagnosed" section: Resource Library --- [Foodborne Illnesses](/foodborne-illnesses) / [Cyclospora](https://marlerclark.com/foodborne-illnesses/cyclospora) / # How is Cyclospora Diagnosed? Cyclosporiasis is usually diagnosed symptomatically in clinical settings, including the presence of watery diarrhea, abdominal cramping, and bloating. In untreated, immunocompetent people, the diarrhea can last from days to weeks to a month or more and can wax and wane, with variable oocyst shedding. Oocysts can continue to be shed (intermittently or continuously) by non-symptomatic people, and symptoms can also persist in the absence of oocysts in feces. In a clinical context, conventional diagnosis usually involves microscopic examination of intestinal tissue biopsy sections, stool samples for the presence of developmental stages of *Cyclospora*, or advanced molecular testing for DNA. Improved specificity and sensitivity have been possible largely through the use of PCR (polymerase chain reaction), which enables the specific amplification of genetic loci from tiny amounts of genomic DNA of *Cyclospora*. Because of the intermittent nature of oocyst shedding and the low numbers of this stage in feces, it is recommended that multiple stool samples be collected at 2-3 day intervals over a period of more than a week, to increase the likelihood of identifying the disease microscopically. ![](https://s3.us-west-2.amazonaws.com/aboutboutlismcom-images/image8.png?1615534372070)Cyclospora under the microscope ![](https://s3.us-west-2.amazonaws.com/aboutboutlismcom-images/image9.jpeg) [ Next: Cyclosporiasis Treatment › ](https://marlerclark.com/foodborne-illnesses/cyclospora/cyclosporiasis-treatment) ### More information about Cyclospora [August 13, 2026 ###### Cyclospora and the 2026 Taylor Farms Outbreak: Questions and Answers Marler Clark represents people sickened in the 2026 Cyclospora outbreak and has filed cases naming Taylor Farms entities as defendants. The answers below are written for people trying to understand ... ](https://marlerclark.com/news_events/cyclospora-and-the-2026-taylor-farms-outbreak-questions-and-answers) [August 08, 2026 ###### FAQ's: The 2026 Cyclospora Outbreak: Questions and Answers for the Public Updated Saturday, August 8, 2026. Everything below is drawn from the federal and state health department pages linked in the answers, and the numbers move, so check the links before ... ](https://marlerclark.com/news_events/faqs-the-2026-cyclospora-outbreak-questions-and-answers-for-the-public) [July 27, 2026 ###### The Cyclospora Lawsuits Have Begun On July 16, health officials linked shredded lettuce sold at US-based Taco Bell restaurants to the cyclosporiasis outbreak. Within hours, the lawsuits began. At least four lawsuits have been filed ... ](https://marlerclark.com/news_events/the-cyclospora-lawsuits-have-begun) [October 23, 2022 ###### A 2020 Cyclospora Outbreak The Centers for Disease Control and Prevention (CDC), along with health departments in 14 states and the Food and Drug Administration (FDA), investigated a national outbreak of Cyclospora in the ... ](https://marlerclark.com/news_events/a-2020-cyclospora-outbreak) [1. View all ](/news_events/outbreaks?illness=cyclospora&year=all) ## All Cyclospora Resources [###### Cyclospora Food Poisoning ](https://marlerclark.com/foodborne-illnesses/cyclospora/what-is-cyclospora) [###### Epidemiology of Cyclospora ](https://marlerclark.com/foodborne-illnesses/cyclospora/epidemiology-of-cyclospora) [###### Cyclospora’s Mode of Infection ](https://marlerclark.com/foodborne-illnesses/cyclospora/cyclosporas-mode-of-infection) [###### Symptoms of Cyclospora Infection ](https://marlerclark.com/foodborne-illnesses/cyclospora/symptoms-of-cyclospora-infection) [###### How is Cyclospora Diagnosed? ](https://marlerclark.com/foodborne-illnesses/cyclospora/how-is-cyclospora-diagnosed) [###### Cyclosporiasis Treatment ](https://marlerclark.com/foodborne-illnesses/cyclospora/cyclosporiasis-treatment) [###### What Are the Serious and Long-term Risks of Cyclospora Infection? ](https://marlerclark.com/foodborne-illnesses/cyclospora/what-are-the-serious-and-long-term-risks-of-cyclospora-infection) [###### Cyclospora Outbreaks ](https://marlerclark.com/foodborne-illnesses/cyclospora/cyclospora-outbreaks) [###### Cyclospora References ](https://marlerclark.com/foodborne-illnesses/cyclospora/cyclospora-references) ### Other foodborne illnesses [E. coli](https://marlerclark.com/foodborne-illnesses/e-coli) [Salmonella](https://marlerclark.com/foodborne-illnesses/salmonella) [Listeria](https://marlerclark.com/foodborne-illnesses/listeria) [Hepatitis A](https://marlerclark.com/foodborne-illnesses/hepatitis-a) [Reactive Arthritis](https://marlerclark.com/foodborne-illnesses/reactive-arthritis) [Guillain-Barre Syndrome](https://marlerclark.com/foodborne-illnesses/guillain-barre-syndrome) [Irritable Bowel Syndrome](https://marlerclark.com/foodborne-illnesses/irritable-bowel-syndrome) [Norovirus](https://marlerclark.com/foodborne-illnesses/norovirus) [Botulism](https://marlerclark.com/foodborne-illnesses/botulism) [Campylobacter](https://marlerclark.com/foodborne-illnesses/campylobacter) [Shigella](https://marlerclark.com/foodborne-illnesses/shigella) [Hemolytic Uremic Syndrome](https://marlerclark.com/foodborne-illnesses/hemolytic-uremic-syndrome)