---
title: "New, Faster Tests Being Developed For Detecting Deadly Botulism Toxin"
date: 2009-05-18T09:43:31-07:00
author: Bill Marler
canonical_url: "https://marlerclark.com/news_events/new-faster-tests-being-developed-for-detecting-deadly-botulism-toxin"
section: News
---
[All News](/news_events) / [Outbreaks](https://marlerclark.com/news_events/outbreaks) /

# New, Faster Tests Being Developed For Detecting Deadly Botulism Toxin

 

 

 The rare, but deadly botulinum toxin is millions of times more poisonous than cyanide. As dangerous as it is, the test for detecting botulinum toxin–an assay requiring the participation of laboratory mice, is neither quick nor easy. It takes from four to eight days, is not portable, nor very affordable.

A new, improved test for detecting what’s known as “serotype A” of the toxin has now been developed by Agricultural Research Service (ARS) biologist Larry H. Stanker and colleagues at the ARS Western Regional Research Center in Albany, Calif.

The new test relies on laboratory built molecules known as monoclonal antibodies, which can bind to the toxin. Assisting the work are biologist Luisa W. Cheng and research associate Miles C. Scotcher.

The botulinum toxin that causes botulism occurs in seven different serotypes–A through G. A and B are culprits in most of the foodborne botulism cases in this country, according to Stanker. The research team now expects to complete assays for detecting serotypes B and E sometime this year.

Safeguard Biosystems, Inc., of San Diego, CA., is packaging two of the serotype A antibodies into a dipstick-style test kit that looks and operates much like a home pregnancy test. The botulinum kit is intended for testing liquids, such as beverages, or clinical specimens, such as blood or urine.

That should be much quicker than waiting around for those lab mice.

ARS, a unit of the United States Department of Agriculture (USDA), has much more about this in its May/June magazine [here](http://www.ars.usda.gov/is/AR/archive/may09/botulism0509.htm).

  

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##### Related Resources

   

 

######  [What is Botulism?](https://marlerclark.com/foodborne-illnesses/botulism/what-is-botulism) 

Botulism is a life-threatening paralytic illness caused by neurotoxins produced by an anaerobic, gram-positive, spore-forming bacterium—Clostridium botulinum. Botulism is a rare disease and only affects a few hundred persons each...

 

######  [Epidemiology and Microbiology of Botulism](https://marlerclark.com/foodborne-illnesses/botulism/epidemiology-and-microbiology-of-botulism) 

C. botulinum bacteria and spores are widely distributed in nature because they are indigenous to soils and waters. They occur in both cultivated and forest soils, bottom sediment of streams...

 

######  [Symptoms of Botulism](https://marlerclark.com/foodborne-illnesses/botulism/symptoms-of-botulism) 

After their ingestion, botulinum neurotoxins are absorbed primarily in the duodenum and jejunum, pass into the bloodstream, and travel to synapses in the nervous system. There, the neurotoxins cause flaccid...

 

######  [Detection and Treatment of Botulism](https://marlerclark.com/foodborne-illnesses/botulism/detection-and-treatment-of-botulism) 

Although botulism can be diagnosed based on clinical symptoms, distinguishing it from other diseases is often difficult, especially in the absence of other known persons affected by the condition. Common...

 

######  [Botulism Outcomes and Long-Term and Permanent Injury](https://marlerclark.com/foodborne-illnesses/botulism/botulism-outcomes-and-long-term-and-permanent-injury) 

In the past 50 years, mortality from botulism has fallen dramatically (from about 50% to 8%) because of advances in supportive care, which is the mainstay of treatment. The respiratory...

 

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