Today Bioniche Life Sciences Inc. a research-based, technology-driven Canadian biopharmaceutical company, announced that positive results were seen in the three latest University of Nebraska feedlot studies utilizing the E. coli O157:H7 cattle vaccine.
In one study, with cattle receiving three doses of vaccine, there were 73% fewer animals detectably shedding E. coli O157:H7 bacteria in their manure. Another three-dose study analyzed colonization in the terminal rectal junction in the cattle, where the bacteria are known to colonize and reproduce. After vaccination, 97% fewer animals had detectable bacterial colonization. A third study, involving 19 feedlots and 21,691 cattle, demonstrated that the vaccine was effective in commercial feedlot settings. In that study, vaccinated cattle were 75% less likely to have detectable bacterial colonization.
This is the third year of data generated through clinical trials of this vaccine, and we are seeing consistently satisfactory results in terms of its effectiveness in feedlot settings where E. coli O157:H7 bacteria are prevalent. The results of the latest University of Nebraska studies will be published in a peer-reviewed journal later this year.
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E. coli Food Poisoning
What is E. coli and how does it cause food poisoning? Escherichia coli (E. coli) is a highly studied, common species of bacteria that belongs to the family Enterobacteriaceae, so...
E. coli O157:H7
E. coli O157:H7 is a foodborne pathogen that causes food poisoning. E. coli O157:H7 is the most commonly identified and the most notorious Shiga toxin-producing E. coli (STEC) serotype in...
Non-O157 STEC
Non-O157 Shiga Toxin-Producing E. coli can also cause food poisoning. E. coli O157:H7 may be the most notorious serotype of Shiga toxin-producing E. coli (STEC), but there are at least...
Sources of E. coli
Where do E. coli O157:H7 and non-O157 Shiga toxin-producing E. coli (STEC) come from? The primary reservoirs, or ultimate sources, of E. coli O157:H7 and non-O157 STEC in nature are...
Transmission of and Infection with E. coli
While many dairy cattle-associated foodborne disease outbreaks are linked to raw milk and other raw dairy products (e.g., cheeses, butter, ice cream), dairy cattle still represent a source of contamination...
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